Marathon runners who suffer cardiac arrest while racing now have twice the survival chance they did two decades ago, thanks to improved emergency response systems.
At a Glance
- Deaths from cardiac arrest during marathons have dropped by half, from 71% in the 2000s to 34% since 2010
- The actual number of cardiac arrests during races has remained steady at approximately 0.6 per 100,000 participants
- Immediate access to CPR and automated external defibrillators (AEDs) has been crucial to improving survival rates
- Men and full marathon participants face higher cardiac arrest risks than women and half-marathon runners
- Coronary artery disease, not thickened heart muscle, is the most common cause of marathon cardiac arrests
Emergency Response Improvements Save Lives
A recent study examining data from 2010 to 2023 has revealed a dramatic improvement in survival rates for marathon runners experiencing cardiac arrest. Despite the constant rate of cardiac incidents during these events over the past two decades, the risk of dying has been cut in half. This improvement stems directly from enhanced emergency medical responses at race venues, including better-trained staff, strategic placement of life-saving equipment, and comprehensive emergency action plans.
Researchers identified 176 cardiac arrests during this period, occurring at a consistent rate of 0.6 per 100,000 participants. What changed significantly was the outcome: while 71% of runners experiencing cardiac arrest during events in the 2000s died, that figure has dropped to just 34% since 2010. This improvement brings marathon survival rates in line with locations known for excellent emergency response capabilities, such as airports and casinos where AEDs are readily available.
We're doing much better preventing sudden cardiac arrest mortality among marathon and half-marathon runnershttps://t.co/lb252R959Q @JAMA_current #ACC25
— Eric Topol (@EricTopol) March 30, 2025
Understanding the Risks
The study revealed important patterns about who faces the highest risks during distance running events. Men experience cardiac arrests during races at significantly higher rates than women. Additionally, full marathons show a higher incidence of cardiac emergencies than half-marathons, likely due to the increased physical demands of the longer distance. These findings help race organizers allocate medical resources most effectively along race routes and target prevention efforts toward those at elevated risk.
Contrary to previous assumptions, researchers discovered that coronary artery disease was the predominant cause of cardiac arrests during these events, rather than hypertrophic cardiomyopathy (thickened heart muscle). This finding challenges conventional wisdom about the primary cardiac risks for runners and suggests that preventative screening approaches may need to be reconsidered to better identify at-risk individuals before they participate in endurance events.
The Critical Role of Immediate Response
The dramatic improvement in survival rates can be directly attributed to better emergency response protocols at marathon events. Every survivor received immediate cardiopulmonary resuscitation (CPR), and the vast majority had quick access to an automated external defibrillator (AED). This highlights the critical importance of both trained responders and strategically placed equipment throughout race courses, particularly in areas where runners are more likely to experience cardiac issues.
The study faced several challenges, including the lack of a central registry for race-related cardiac events. Researchers collected data through multiple channels, including race directors, media reports, and interviews with survivors or next of kin. Despite these limitations, the findings provide compelling evidence that targeted emergency planning with an emphasis on immediate response capabilities saves lives during these increasingly popular events.
Future Directions for Runner Safety
With more than 29 million people having completed marathons in the U.S. between 2010 and 2023—a threefold increase from the previous decade—the importance of effective cardiac emergency planning continues to grow. Medical professionals are now advocating for expanded efforts to identify at-risk individuals before they participate in endurance events, wider CPR education among both race staff and participants, and even more comprehensive race-day medical preparedness.
While cardiac arrests during marathons remain relatively rare, each incident offers an opportunity to refine safety protocols. The study’s findings emphasize that with proper preparation and immediate response, these events don’t have to be fatal. For runners over 40 concerned about cardiac health, experts recommend discussing any family history of heart disease with healthcare providers before participating in endurance events and being aware of warning signs that might indicate underlying cardiac issues.
Sources:
https://www.acc.org/Latest-in-Cardiology/Journal-Scans/2025/03/24/16/30/sun-5pm-racer-acc-2025
https://pubmed.ncbi.nlm.nih.gov/8800121
https://www.sciencedaily.com/releases/2025/03/250330223449.htm
https://jamanetwork.com/journals/jama/fullarticle/2832121
https://www.jwatch.org/na58630/2025/04/01/update-sudden-cardiac-arrests-marathon-runners
https://news.emory.edu/stories/2025/03/er_cardiac_arrest_31_03_2025/story.html